Name | glycodeoxycholic acid sodium |
Synonyms | GDCA GDCA, SODIUM SALT Glycodeoxycholic Acid, Sodiu glycodeoxycholic acid sodium Glycodeoxycholic acid sodium salt GLYCODEOXYCHOLIC ACID SODIUM SALT 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL N-(CARBOXYMETHYL)-AMIDE SODIUM SALT 5BETA-CHOLAN-24-OIC ACID N-[CARBOXYMETHYL]AMIDE-3ALPHA,12ALPHA-DIOL SODIUM SALT 3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-(CARBOXYMETHYL)-AMIDE SODIUM SALT glycine, N-[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]-, monosodium salt |
CAS | 16409-34-0 |
EINECS | 240-455-4 |
InChI | InChI=1/C26H43NO5.Na/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3;/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-;/m1./s1 |
InChIKey | VMSNAUAEKXEYGP-YEUHZSMFSA-M |
Molecular Formula | C26H42NNaO5 |
Molar Mass | 471.61 |
Melting Point | 245-250 °C |
Boling Point | 655.6°C at 760 mmHg |
Flash Point | 350.3°C |
Solubility | H2O: 0.1 M at 20 °C, clear, colorless |
Vapor Presure | 5.74E-20mmHg at 25°C |
Appearance | White solid |
Color | White to Off-White |
Storage Condition | Inert atmosphere,2-8°C |
Stability | Hygroscopic |
MDL | MFCD00036742 |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | MB9670000 |
HS Code | 29221990 |
Reference Show more | 1. Cao Yan, Song Qingqing, Li Jun, et al. Analysis of Bile Acids in Yak Gallbladder [J]. Chinese Journal of Traditional Chinese Medicine, Volume 44, Issue 12, 2019, pp. 2538-2543, MEDLINE ISTIC PKU CSCD CA BP, 2019. 2. [IF = 5.878] Min Wen et al."Geniposide suppresses liver injury in a mouse model of DDC-induced sclerosing cholangitis." Phytother Res. 2021 Jul;35(7):3799-3811 |
Introduction | Sodium deoxyglycholate is a kind of bile acid, which is combined with glycine or taurine to form glycyl in bile. It exists in the form of deoxycholic acid or sodium taurodeoxycholate, which is a bile acid that forms many organic compounds and stable molecular compounds. |
Effect | Sodium deoxyglycholate is easily soluble in water and has a strong surface activity. It can be used to destroy cells and extract enzymes. Sodium deoxyglycholate is not directly biosynthesized by cholesterol, but synthesized from bile acid through metabolism by intestinal bacteria. |
Biological activity | Glycochenodeoxycholic acid (GCDC, Glycodeoxycholate, Deoxycholylglycine) is a bile salt that is used as an anionic detergent to dissolve lipids. |